PC 01.01 SABR as First Line Treatment Option

Cinacalcet as first-line treatment for calciphylaxis.

Some Explicitly Solvable SABR and Multiscale SABR Models: Option Pricing and Calibration

A multiscale SABR model that describes the dynamics of forward prices/rates is presented. New closed form formulae for the transition probability density functions of the normal and lognormal SABR and multiscale SABR models and for the prices of the corresponding European call and put options are deduced. The technique used to obtain these formulae is rather general and can be used to study oth...

Fomepizole as a First-line Treatment of Patients with Methanol Poisoning

Methanol is responsible for a life-threatening poisoning. Fomepizole, a potent alcohol dehydrogenase inhibitor, is an efficient and safe antidote that prevents or reduces toxic methanol metabolism. Although no study has compared its efficacy with ethanol, fomepizole is recommended as a first-line antidote. Treatment should be started as soon as possible, based on history and initial findings in...

The COS method for option valuation under the SABR dynamics

In this paper,we consider theCOSmethod for pricing European andBermudan options under the stochastic alpha beta rho (SABR) model. In the COS pricing method, we make use of the characteristic function of the discrete forward process. We observe second-order convergence by using a second-order Taylor scheme in the discretization, or by using Richardson extrapolation in combination with a Euler–Ma...

Comparison of bismuth-containing quadruple and concomitant therapies as a first-line treatment option for Helicobacter pylori.

BACKGROUND/AIMS Helicobacter pylori eradication rates with standard triple regimens are worsening, and alternative treatments are urgently needed in some populations. The present study aimed to compare the efficacy of bismuth-based quadruple and concomitant regimens. METHODS Consecutive Helicobacter pylori-positive patients with non-ulcer dyspepsia were randomized to receive one of two regime...